Product Name	LPCAT1
Chinese Name	溶血卵磷脂酰基转移酶1单克隆抗体
Alias	PCAT1_HUMAN; Lysophosphatidylcholine acyltransferase 1; AYTL2; PFAAP3; EC:2.3.1.23; LPC acyltransferase 1; LPCAT-1; LysoPC acyltransferase 1; 1-acylglycerol-3-phosphate O-acyltransferase. EC:2.3.1.51; 1-acylglycerophosphocholine O-acyltransferase; 1-alkenylglycerophosphocholine O-acyltransferase. EC:2.3.1.25; 1-alkylglycerophosphocholine O-acetyltransferase. EC:2.3.1.67; Acetyl-CoA:lyso-platelet-activating factor acetyltransferase (Acetyl-CoA:lyso-PAF acetyltransferase; Lyso-PAF acetyltransferase; LysoPAFAT);
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	D10F11
React Species	Human,Mouse
Applications	WB=1:500-1000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	59kDa
Detection molecular weight	59 kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG2B/Kappa
Purification	Affinity purified by Protein G
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Lysophosphatidylcholine (LPC) acyltransferase (LPCAT; EC 2.3.1.23) catalyzes the conversion of LPC to phosphatidylcholine (PC) in the remodeling pathway of PC biosynthesis (Nakanishi et al., 2006 [PubMed 16704971]).[supplied by OMIM, May 2008] SWISS: Q8NF37 Gene ID: 79888 Database links: Entrez Gene: 79888 Human Entrez Gene: 210992 Mouse SwissProt: Q8NF37 Human SwissProt: Q3TFD2 Mouse It has acyltransferase activity. It exhibits acetyltransferase activity, and the activity is not dependent on calcium. It catalyzes the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC). It catalyzes the conversion of 1-acyl-sn-glycero-3-phosphate (lysophosphatidic acid or LPA) to 1,2-diacyl-sn-glycero-3-phosphate (phosphatidic acid or PA). By incorporating an acyl moiety at the sn-2 position of the glycerol backbone, it shows a clear preference for saturated fatty acyl-CoAs and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively. It is involved in the biosynthesis of platelet-activating factor (PAF) by catalyzing the conversion of the PAF precursor 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) to 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). It may play a key role in respiratory physiology by synthesizing phosphatidylcholine in pulmonary surfactant. It is involved in regulating the number and size of lipid droplets.

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