Fms-related tyrosine kinase 3 ligand (Flt3L), Human, Recombinant  Brief introduction:Fms associated tyrosine kinase 3 ligand (Flt3L) is a growth factor that stimulates proliferation and differentiation of hematopoietic pluripotent stem cells and promotes proliferation of NK cells and dendritic cell subsets by binding to other growth factors. Flt3L is produced by T cells and stromal fibroblasts and targets a variety of cells, including hematopoietic stem cells, B cells, T cells, dendritic cells, and NK cells. Flt3L binds to the homologous tyrosine kinase receptor Flt3 to activate the JAK/STAT signaling pathway.Flt3L is a hematopoietic four-helical bundle cytokine homologous to stem cell factor (SCF) and colony-stimulating factor 1 (CSF-1) with four conserved cysteines and two glycosylation sites. The length of the extracellular part of Flt3L is about 160 amino acid residues, and the length of the cytoplasmic segment is about 20-30 amino acid residues.Aliases: Fms-related tyrosine kinase 3 ligand (Flt3L), Human, Recombinant; Flt3 ligand;  FL;  Flt3LG;  SL cytokinePhysical properties and indexes:Purity: >95%Endotoxin: <0.2 EU/μgTiter: >1 x 106units/mgExpression host: CHOSource: HumanPurification Method: purification by chromatographyCharacter: This product is white loose bodyStability: The freeze-dried powder can be stored at -20℃ for 12 months, the dissolved liquid can be stored at -20℃ for 2 months, and at 4℃ for 1 week, and avoid repeated freeze-thawAmino acid sequence:TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE  QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTAUsage and Description: Scientific research reagent, widely used in cell biology, pharmacology and other scientific research, is strictly prohibited for human body. Flt3L can promote the generation and differentiation of hematopoietic stem cells and their progenitor cells. Hfs-associated tyrosine kinase 3 ligand mRNA is highly expressed in certain tissues, including peripheral blood mononuclear cells, heart, placenta, lung, spleen, and thymus tissues, and to some extent in non-hematopoietic tissues, including prostate, testis, ovary, intestine, liver, kidney, and skeletal muscle. 

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