Product Name	Recombinant Rabbit Anti-MyD88 Monoclonal Antibody
Cat No.	SLA0810M
Alias	IMD68; MYD88D; WM1; MYD88_HUMAN; MYD88; MYD88_MOUSE; MYD88_RAT; MYD88 innate immune signal transduction adaptor; myeloid differentiation primary response gene (88); myeloid differentiation primary response 88; TLR adaptor MYD88
Host Species	Mouse
Clonality	Monoclonal
Clone No.	12E9
React Species	Human,Mouse,Rat
Applications	IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Synthesized peptide derived from human Myd88
Purification	Affinity-chromatography using specific immunogen.
Predicted MW.	33 kDa
Swiss-Prot	Q99836
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq , Feb 2010]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.

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