Product Name	NR1H4 | FXR mAb
Cat No.	SLM-51869M
Chinese Name
Alias	BAR; FXR; HRR-1; HRR1; PFIC5; RIP14; Rxrip14; NR1H4_HUMAN; NR1H4; Farnesoid X-activated receptor; Farnesol receptor HRR-1; Nuclear receptor subfamily 1 group H member 4; Retinoid X receptor-interacting protein 14 (RXR-interacting protein 14); Q3V1T8_MOUSE; Retinoid X receptor-interacting protein 14; NR1H4_MOUSE; Q5XI75_RAT; NR1H4_RAT; nuclear receptor subfamily 1, group H, member 4; farnesoid X receptor; bile acid receptor
Host Species
Isotype	igg2a/kappa
Clonality	Monoclonal
Clone No.	5H3
React Species	Human,Mouse
Applications	WB (1:500-2000) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	NR1H4 protein
Purification	affinity purified by Protein G
Concentration	1mg/ml
Predicted MW.	56 kDa
Observed MW.
Subcellular Location	Nucleus
Gene ID
Swiss-Prot	Q96RI1
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids , and when bound to bile acids , binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq , Feb 2016]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.