Product Name	Recombinant Rabbit Anti-MCM2 Monoclonal Antibody
Cat No.	SLA0777M
Alias	BM28; CCNL1; CDCL1; D3S3194; DFNA70; MITOTIN; cdc19; Mcmd2; mKIAA0030; MCM2_HUMAN; MCM2; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28; 3.6.4.12; KIAA0030; MCM2_MOUSE; minichromosome maintenance complex component 2; minichromosome maintenance deficient (S. cerevisiae) 2 (mitotin); MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)
Host Species	Mouse
Isotype	IgG1/Kappa
Clonality	Monoclonal
Clone No.	3A5
React Species	Human,Mouse
Applications	WB (1:500-2000) IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Synthesized peptide derived from human MCM2
Purification	affinity purified by Protein G
Predicted MW.	102 kDa
Swiss-Prot	P49736
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4 , 6 , and 7 , and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated , and thus regulated by , protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found , but the full-length nature of some variants has not been defined. [provided by RefSeq , Oct 2012]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.