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Product Name Recombinant Rabbit Anti-MAPK9 Monoclonal Antibody Cat No. SLA0775M Alias JNK-55; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; PRKM9; SAPK; SAPK1a; p54a; p54aSAPK; MK09_HUMAN; MAPK9; MAP kinase 9; MAPK 9; Stress-activated protein kinase 1a (SAPK1a); Stress-activated protein kinase JNK2; c-Jun N-terminal kinase 2; 2.7.11.24; MK09_MOUSE; MK09_RAT; SAPK-alpha; p54-alpha; mitogen-activated protein kinase 9; Jun kinase Host Species Mouse Clonality Monoclonal Clone No. 6D4 React Species Human,Mouse,Rat Applications IHC-P (1:100-500)
IHC-F (1:100-500)
IF (1:100-500)
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.Immunogen Synthesized peptide derived from human JNK2 Purification Affinity-chromatography using specific immunogen. Concentration 1mg/ml Predicted MW. 48 kDa Swiss-Prot P45984 Storage 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.Background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals , and are involved in a wide variety of cellular processes such as proliferation , differentiation , transcription regulation and development. This kinase targets specific transcription factors , and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8 , both of which are involved in UV radiation induced apoptosis , thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53 , and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's counterpart suggest a key role in T-cell differentiation. Several alternative Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.
+86 571 56623320
[email protected]
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