Product Name	Recombinant Rabbit Anti-DUSP9 Monoclonal Antibody
Cat No.	SLA3516M
Alias	MKP-4; MKP4; Mpk4; Pyst3; DUS9_HUMAN; DUSP9; Mitogen-activated protein kinase phosphatase 4 (MAP kinase phosphatase 4 | MKP-4); 3.1.3.16; 3.1.3.48; dual specificity phosphatase 9; map kinase phosphatase 4; Dual specificity protein phosphatase 9; Mitogen-activated protein kinase phosphatase 4
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	5D8
React Species	Human
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	1852
Swiss-Prot	Q99956
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progr
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.