Product Name	Recombinant Rabbit Anti-SCARB1 Monoclonal Antibody
Cat No.	SLA3486M
Alias	CD36L1; CLA-1; CLA1; HDLCQ6; HDLQTL6; SR-BI; SRB1; AMRF; CD36L2; EPM4; HLGP85; LGP85; LIMP-2; LIMPII; SR-BII; 9330185J12Rik; LIMP II; MLGP85; CD36; Chohd1; D5Ertd460e; Hdlq1; Hlb398; SR-B1; SRBI; mSR-BI; SCRB2_HUMAN; SCARB2; 85 kDa lysosomal membrane sialoglycoprotein (LGP85); CD36 antigen-like 2; Lysosome membrane protein II (LIMP II); Scavenger receptor class B member 2; LIMP2; SCRB1_HUMAN; SCARB1; CD36 and LIMPII analogous 1 (CLA-1); CD36 antigen-like 1; Collagen type I receptor, thrombospondin receptor-like 1; SCRB2_MOUSE; SCRB1_MOUSE; SCRB2_RAT; SCRB1_RAT; scavenger receptor class B member 1; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; scavenger receptor class B, member 1; Scavenger receptor class B member 1 (SRB1) (CD36 and LIMPII analogous 1) (CLA-1) (CD36 antigen-like 1) (Collagen type I receptor, thrombospondin receptor-like 1) (SR-BI) (CD antigen CD36)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	8H0
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	949
Swiss-Prot	Q14108
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI (Scavenger Receptor BI) protein binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland. Scavenging Receptor SR-BI plays a critical role in HCV attachment and/or cell entry by interacting with HCV E1/E2 glycoproteins heterodimer.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.