Product Name	Recombinant Rabbit Anti-MRE11 Monoclonal Antibody
Cat No.	SLA3327M
Alias	ATLD; HNGS1; MRE11A; MRE11B; Mre11; MRE11_HUMAN; Meiotic recombination 11 homolog 1 (MRE11 homolog 1); Meiotic recombination 11 homolog A (MRE11 homolog A); 3.1.-.-; MRE11_MOUSE; Meiotic recombination 11 homolog A (MRE11 homolog A | MmMRE11A); MRE11_RAT; Double-strand break repair protein MRE11A; MRE11 double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease; MRE11 meiotic recombination 11 homolog A (S. cerevisiae); MRE11 homolog A, double strand break repair nuclease; AT-like disease; Meiotic recombination 11 homolog 1; MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog A
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	5G4
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	4361
Swiss-Prot	P49959
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.

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