Product Name	Recombinant Rabbit Anti-TGFBR2 Monoclonal Antibody
Cat No.	SLA3298M
Alias	AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TBR-ii; TBRII; TGFR-2; TGFbeta-RII; tbetaR-II; 1110020H15Rik; DNIIR; RIIDN; TbetaRII; TGFR2_HUMAN; TGFBR2; TGF-beta type II receptor; Transforming growth factor-beta receptor type II (TGF-beta receptor type II | TbetaR-II); 2.7.11.30; TGFR2_MOUSE; transforming growth factor beta receptor 2; transforming growth factor, beta receptor II (70/80kDa); transforming growth factor beta receptor II; TGF-beta receptor type-2; Transforming growth factor-beta receptor type II; TGF-beta receptor type II
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	1E4
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	7048
Swiss-Prot	P37173
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.