Product Name	Recombinant Rabbit Anti-FLT3 Monoclonal Antibody
Cat No.	SLA3296M
Alias	CD135; FLK-2; FLK2; STK1; B230315G04; Flt-3; Ly72; wmfl; FLT3_HUMAN; FLT3; FL cytokine receptor; Fetal liver kinase-2 (FLK-2); Fms-like tyrosine kinase 3 (FLT-3); Stem cell tyrosine kinase 1 (STK-1); 2.7.10.1; FLT3_MOUSE; Fetal liver kinase 2 (FLK-2); Tyrosine-protein kinase receptor flk-2; fms related receptor tyrosine kinase 3; fms-related tyrosine kinase 3; fms related tyrosine kinase 3; Receptor-type tyrosine-protein kinase FLT3; Fetal liver kinase-2; Fms-like tyrosine kinase 3; Stem cell tyrosine kinase 1; STK-1; CD antigen CD135
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	5C6
React Species	Human,Mouse
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	2322
Swiss-Prot	P36888
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.