Product Name	Recombinant Rabbit Anti-FGFR2 Monoclonal Antibody
Cat No.	SLA3253M
Alias	BBDS; BEK; BFR-1; CD332; CEK3; CFD1; ECT1; JWS; K-SAM; KGFR; TK14; TK25; Fgfr-2; Fgfr-7; Fgfr2b; Fgfr7; KGFRTr; svs; FGFR2_HUMAN; FGFR2; K-sam (KGFR); Keratinocyte growth factor receptor; 2.7.10.1; KSAM; FGFR2_MOUSE; Keratinocyte growth factor receptor (KGFR); fibroblast growth factor receptor 2; bacteria-expressed kinase; craniofacial dysostosis 1; Jackson-Weiss syndrome; Crouzon syndrome; Pfeiffer syndrome; CD antigen CD332
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	3E3
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	2263
Swiss-Prot	P21802
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, C
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.