Product Name	Recombinant Rabbit Anti-BMPR2 Monoclonal Antibody
Cat No.	SLA3407M
Alias	BMPR-II; BMPR3; BMR2; BRK-3; POVD1; PPH1; T-ALK; 2610024H22Rik; BMP-2; BMPR-2; BMPRII; Gm20272; BMPR2_HUMAN; BMPR2; BMP type-2 receptor; Bone morphogenetic protein receptor type II (BMP type II receptor | BMPR-II); 2.7.11.30; BMPR2_MOUSE; bone morphogenetic protein receptor type 2; primary pulmonary hypertension 1; bone morphogenetic protein receptor, type II (serine/threonine kinase); bone morphogenetic protein receptor type II; Bone morphogenetic protein receptor type-2; BMP type II receptor
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	3E9
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	659
Swiss-Prot	Q13873
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disea
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.