Product Name	Recombinant Rabbit Anti-IL6R Monoclonal Antibody
Cat No.	SLA3211M
Alias	CD126; HIES5; IL-1Ra; IL-6R; IL-6R-1; IL-6RA; IL6Q; IL6QTL; IL6RA; IL6RQ; gp80; IL-6R-alpha; Il6r; IL6RA_HUMAN; IL-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R 1; Membrane glycoprotein 80 (gp80); IL6RA_MOUSE; IL6RA_RAT; interleukin 6 receptor; membrane glycoprotein 80; interleukin 6 receptor subunit alpha; Interleukin-6 receptor subunit alpha
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	11C9
React Species	Human
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	3570
Swiss-Prot	P08887
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.