Product Name	Recombinant Rabbit Anti-AXIN1 Monoclonal Antibody
Cat No.	SLA3151M
Alias	AXIN; CMDOH; PPP1R49; AXIN1-RGS; axin-1; Fu; Kb; Ki; fused; kinky; knobbly; AXIN1_CHICK; AXIN1; Axis inhibition protein 1; AXN; AXIN1_HUMAN; Axis inhibition protein 1 (hAxin); AXIN1_MOUSE; Protein Fused; AXIN1_RAT; Axis inhibition protein 1 (rAxin); axin 1; protein phosphatase 1, regulatory subunit 49; Axin-1 (Axis inhibition protein 1) (hAxin)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	3F1
React Species	Human,Mouse
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	8312
Swiss-Prot	O15169
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.

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