Product Name	Recombinant Rabbit Anti-DCX Monoclonal Antibody
Cat No.	SLA2887M
Chinese Name	双皮质素重组兔单抗
Alias	DBCN; DC; LISX; SCLH; XLIS; Dbct; DCX_HUMAN; DCX; Doublin; Lissencephalin-X (Lis-X); DCX_MOUSE; Dcn; DCX_RAT; doublecortin; doublecortex; lissencephaly, X-linked (doublecortin)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	5H2
React Species	Mouse,Rat
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human Doublin
Purification	affinity purified by Protein A
Predicted MW.	41 kDa
Observed MW.	42 kDa
Subcellular Location	Cytoplasm
Gene ID	1641
Swiss-Prot	O43602
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Doublecortin (DCX) is a microtubule-associated protein expressed almost exclusively in immature neurons. Neuronal precursors begin to express DCX shortly after exiting the cell cycle, and continue to express DCX for 2-3 weeks as the cells mature into neurons. Downregulation of DCX begins after 2 weeks, and occurs at the same time that these cells begin to express, a marker for mature neurons. Due to the nearly exclusive expression of DCX in developing neurons, this protein has been used increasingly as a marker for neurogenesis. Indeed, the levels of DCX expression increase in response to exercise, which occurs in parallel with increased BrdU labelling, currently a "gold standard" in measuring neurogenesis.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.

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