Product Name	Recombinant Rabbit Anti-PUM1 Monoclonal Antibody
Cat No.	SLA1923M
Chinese Name	PUM1蛋白重组兔单抗
Alias	HSPUM; NEDMSF; PUMH; PUMH1; PUML1; SCA47; Pumm; mKIAA0099; PUM1_HUMAN; PUM1; Pumilio-1; KIAA0099; PUM1_MOUSE; pumilio RNA binding family member 1; pumilio homolog 1 (Drosophila)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human Pumilio 1
Purification	affinity purified by Protein A
Predicted MW.	126 kDa
Observed MW.	140 kDa
Subcellular Location	Cytoplasm
Gene ID	9698
Swiss-Prot	Q14671
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE).Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.