Product Name	Recombinant Rabbit Anti-GBP2 Monoclonal Antibody
Cat No.	SLA1065M
Chinese Name	G蛋白结合蛋白2单克隆抗体
Alias	GBP2_HUMAN; GBP2; GTP-binding protein 2 (GBP-2 | HuGBP-2); Guanine nucleotide-binding protein 2; Interferon-induced guanylate-binding protein 2; 3.6.5.-; GBP2_MOUSE; GTP-binding protein 2 (GBP-2 | mGBP-2 | mGBP2); GBP2_RAT; GTP-binding protein 2 (GBP-2); p67; guanylate binding protein 2; guanylate binding protein 2, interferon-inducible
Host Species	Mouse
Isotype	IgG2b
Clonality	Monoclonal
React Species	Human
Applications	WB (1:500-2000) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant protein of human GBP2
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	67 kDa
Subcellular Location	Nucleus
Gene ID	2634
Swiss-Prot	P32456
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Guanylate-binding proteins, GBP1 and GBP2 are GTP-binding proteins with a high-turnover GTPase activity and an antiviral effect (1-4). GBP1 mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus and plays a role in the IFN-mediated antiviral response against these viruses (4). GBP1 and GBP2 belong to a group of large GTP-binding proteins with a high concentration-dependent GTPase activity that have the common ability to undergo oligomerization (1). GBP1 and GBP2 are bone marrow-derived GTPases encoded by interferon-activated genes and are inducible following IFN treatment (2,3). Specifically, GBP1 is expressed in cultured mammary epithelial tumor cell lines after treatment with IFN-gamma and LPS (5).
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.