Product Name	Recombinant Rabbit Anti-PLAUR Monoclonal Antibody
Cat No.	SLA0455M
Chinese Name	尿激酶型纤溶酶原激活因子受体（CD87）单克隆抗体
Alias	CD87; U-PAR; UPAR; URKR; Par; Plaur3; uPAR-2; uPAR-3; UPAR_HUMAN; PLAUR; Monocyte activation antigen Mo3; MO3; UPAR_MOUSE; UPAR_RAT; plasminogen activator, urokinase receptor; urokinase-type plasminogen activator (uPA) receptor; urokinase plasminogen activator surface receptor
Host Species	Mouse
Isotype	IgG
Clonality	Monoclonal
React Species	Human
Applications	WB (1:500-2000) IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant human PLAUR protein
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	31 kDa
Subcellular Location	Membrane
Gene ID	5329
Swiss-Prot	Q03405
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol(GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq].
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.