Product Name	Recombinant Rabbit Anti-CD80 Monoclonal Antibody
Cat No.	SLA0385M
Chinese Name	小鼠CD80单克隆抗体
Alias	B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7; B71; Cd28l; Ly-53; Ly53; MIC17; TSA1; CD80_HUMAN; CD80; Activation B7-1 antigen; CTLA-4 counter-receptor B7.1 (B7); CD80_MOUSE; Activation B7-1 antigen (B7); CD80 molecule; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); B-lymphocyte activation antigen B7
Host Species	Rat
Isotype	Rat IgG2a, k
Clonality	Monoclonal
Clone No.	8H2
Applications	Flow-Cyt (1:50-100) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein G
Predicted MW.	32 kDa
Observed MW.	60 kDa
Subcellular Location	Membrane
Storage	0.01M PBS (pH7.4). Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.