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Product Name Recombinant Rabbit Anti-RAD51 Monoclonal Antibody Cat No. SLA0710M Chinese Name Rad51单克隆抗体 Alias BRCC5; FANCR; HRAD51; HsRad51; HsT16930; MRMV2; RAD51A; RECA; RGD1563603; RAD51_HUMAN; RAD51; RAD51 homolog A; RAD51_MOUSE; RAD51 recombinase; RAD51 (S. cerevisiae) homolog (E coli RecA homolog); RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae); RAD51 homolog (S. cerevisiae); BRCA1/BRCA2-containing complex, subunit 5 Host Species Mouse Isotype IgG Clonality Monoclonal Clone No. 3G10 React Species Human,Mouse,Rat Applications WB (1:500-2000)
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.Immunogen Recombination human RAD51 protein Purification affinity purified by Protein G Concentration 1mg/ml Predicted MW. 37 kDa Subcellular Location Nucleus Gene ID 5888 Swiss-Prot Q06609 Storage 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.Background The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. Transcript variants utilizing alternative polyA signals exist. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.
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- Price: USD, per unit (50ul / 100ul)
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[email protected]
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