Product Name	Recombinant Rabbit Anti-AKT (p-S472/S473/S474) Monoclonal Antibody
Cat No.	SLA0912M
Chinese Name	磷酸化蛋白激酶B2重组兔单抗
Alias	AKT2 (phospho-S474); p-AKT2; phospho-AKT2; AKT2 (phospho-Ser474); HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA; 2410016A19Rik; PKB; AKT2_HUMAN; AKT2; Protein kinase Akt-2; Protein kinase B beta (PKB beta); RAC protein kinase beta (RAC-PK-beta); 2.7.11.1; AKT2_MOUSE; RAC-PK-beta; AKT2_RAT;
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	5G5
React Species	Human
Applications	WB (1:500-2000) Flow-Cyt () Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated Synthesised phosphopeptide derived from human AKT2 around the phosphorylation site of Ser474
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	56 kDa
Observed MW.	60 kDa
Subcellular Location	Nucleus
Gene ID	208
Swiss-Prot	P31751
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.