Product Name	Recombinant Rabbit Anti-STING1 Monoclonal Antibody
Cat No.	SLA1009M
Chinese Name	磷酸化跨膜蛋白173重组兔单抗
Alias	ERIS; MITA; MPYS; NET23; SAVI; STING; STING-beta; TMEM173; hMITA; hSTING; STING_HUMAN; STING1; Endoplasmic reticulum interferon stimulator (ERIS); Mediator of IRF3 activation (hMITA); Transmembrane protein 173; stimulator of interferon response cGAMP interactor 1; stimulator of interferon genes; endoplasmic reticulum IFN stimulator; STING | TMEM173 (phospho-S365); p-TMEM173; phospho-TMEM173; p-STING; STING | TMEM173 (phospho-Ser365)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	5H6
React Species	Human
Applications	IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated Synthesised phosphopeptide derived from human STING1 around the phosphorylation site of Ser366
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	42 kDa
Subcellular Location	Cytoplasm
Gene ID	340061
Swiss-Prot	Q86WV6
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.