Product Name	Recombinant Rabbit Anti-P2RX7 Monoclonal Antibody
Cat No.	SLA0989M
Chinese Name	嘌呤受体P2X7重组兔单抗
Alias	P2X7; P2X(7); P2X7R; P2RX7_HUMAN; P2RX7; ATP receptor; P2Z receptor; Purinergic receptor; P2RX7_MOUSE; P2RX7_RAT; purinergic receptor P2X 7; purinergic receptor P2X, ligand-gated ion channel, 7
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	12A3
React Species	Mouse
Applications	WB (1:500-2000) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human P2RX7
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	69 kDa
Observed MW.	78 kDa
Subcellular Location	Membrane
Gene ID	5027
Swiss-Prot	Q99572
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.