Product Name	Recombinant Rabbit Anti-UBA3 Monoclonal Antibody
Cat No.	SLA2527M
Chinese Name	UBA3重组兔单抗
Alias	UBA3_HUMAN; UBA3; NEDD8-activating enzyme E1C; Ubiquitin-activating enzyme E1C; Ubiquitin-like modifier-activating enzyme 3 (Ubiquitin-activating enzyme 3); 6.2.1.64; UBE1C; NAE2; hUBA3; ubiquitin like modifier activating enzyme 3; ubiquitin-activating enzyme E1C (homologous to yeast UBA3); ubiquitin-activating enzyme E1C (UBA3 homolog, yeast); ubiquitin-like modifier activating enzyme 3; NEDD8-activating enzyme E1 catalytic subunit; NEDD8-activating enzyme E1 subunit 2
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	9F4
React Species	Human,Mouse
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human UBA3
Purification	affinity purified by Protein A
Predicted MW.	52 kDa
Observed MW.	50 kDa
Gene ID	9039
Swiss-Prot	Q8TBC4
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.