Product Name	Recombinant Rabbit Anti-CASP7 Monoclonal Antibody
Cat No.	SLA0930M
Chinese Name	半胱胺酸蛋白酶-7重组鼠单抗
Alias	CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3; ICE-IAP3; caspase-7; mCASP-7; CASP7_MESAU; CASP7; Apoptotic protease Mch-3; ICE-like apoptotic protease 3 (ICE-LAP3); SREBP cleavage activity 2 (SCA-2); 3.4.22.60; CASP7_HUMAN; CASP7_MOUSE; Cysteine protease LICE2; caspase 7; caspase 7, apoptosis-related cysteine protease; caspase 7, apoptosis-related cysteine peptidase
Host Species	Mouse
Isotype	IgG1
Clonality	Monoclonal
Clone No.	SB66
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant Human Caspase 7 protein
Purification	Affinity Purification
Predicted MW.	34 kDa
Observed MW.	36 kDa
Subcellular Location	Nucleus
Gene ID	840
Swiss-Prot	P55210
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death. Cleaves phospholipid scramblase proteins XKR4, XKR8 and XKR9 .
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.