Product Name	Recombinant Rabbit Anti-PRKCZ Monoclonal Antibody
Cat No.	SLA1138M
Chinese Name	蛋白激酶C zeta重组兔单抗
Alias	PKC-ZETA; PKC2; Pkcz; aPKCzeta; nPKC-zeta; zetaPKC; 14-3-3-zetaisoform; r14-3-3; KPCZ_HUMAN; PRKCZ; 2.7.11.13; KPCZ_MOUSE; KPCZ_RAT; protein kinase C zeta; protein kinase C, zeta
Host Species	Rabbit
Clonality	Monoclonal
Clone No.	7H17
React Species	Human,Mouse
Applications	WB (1:500-1000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human PKC zeta
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	66 kDa
Observed MW.	72 kDa
Subcellular Location	Cytoplasm
Gene ID	5590
Swiss-Prot	Q05513
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.