Product Name	Recombinant Rabbit Anti-Il1b Monoclonal Antibody
Cat No.	SLA0975M
Chinese Name	白介素1β/IL-1β单克隆抗体
Alias	IL-1; IL1-BETA; IL1F2; IL1beta; IL-1beta; Il-1b; IL-1F2; IL1B_HUMAN; IL1B; IL-1 beta; Catabolin; IL1B_MOUSE; IL1B_RAT; interleukin 1 beta; Interleukin-1 beta; IL-1β; IL1β
Host Species	Mouse
Isotype	IgG1, k
Clonality	Monoclonal
Clone No.	2H12
React Species	Human
Applications	IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant rat IL-1 beta protein
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	32 kDa
Subcellular Location	Secreted
Gene ID	3553
Swiss-Prot	P01584
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.