Product Name	SREBF2 | SREBP2 Recombinant Rabbit mAb
Cat No.	SLM-63681R
Alias	SREBP-2; SREBP2; bHLHd2; SREBP2gc; lop13; nuc; Srebf2_retired; XELAEV_18023633mg; SRBP2_CRIGR; SREBF2; Sterol regulatory element-binding transcription factor 2; SRBP2_HUMAN; Class D basic helix-loop-helix protein 2 (bHLHd2); SRBP2_MOUSE; SRBP2_RAT; SRBP2_XENLA; sterol regulatory element binding transcription factor 2; Sterol regulatory element-binding protein 2; Sterol regulatory element-binding protein 2 (SREBP-2) (Class D basic helix-loop-helix protein 2) (bHLHd2) (Sterol regulatory element-binding transcription factor 2) [Cleaved into: Processed sterol regulatory element-binding protein 2]; SRBP2; Class D basic helix-loop-helix protein 2; [Cleaved into: Processed sterol regulatory element-binding protein 2]
Host Species	Rabbit
Isotype	IgG
Clonality	Recombinant
Clone No.	11B1
React Species	Human,Rat
Applications	IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Subcellular Location	Nucleus
Gene ID	6721
Swiss-Prot	Q12772
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Paraformaldehyde-fixed, paraffin embedded Rat Ovary; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with SREBF2 | SREBP2 Monoclonal Antibody, Unconjugated (SLM-63681R) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.	Figure 2. Paraformaldehyde-fixed, paraffin embedded Rat Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with SREBF2 | SREBP2 Monoclonal Antibody, Unconjugated (SLM-63681R) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.
Figure 3. Paraformaldehyde-fixed, paraffin embedded Human Liver Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with SREBF2 | SREBP2 Monoclonal Antibody, Unconjugated (SLM-63681R) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.	Figure 4. Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with SREBF2 | SREBP2 Monoclonal Antibody, Unconjugated (SLM-63681R) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.