Product Name	Recombinant Rabbit Anti-MAP3K4 Monoclonal Antibody
Cat No.	SLA2494M
Chinese Name	丝裂原活化蛋白激酶激酶激酶4重组兔单抗
Alias	MAPKKK4; MEKK 4; MEKK4; MTK1; PRO0412; D17Rp17; D17Rp17e; Mek4b; RP17; Rp17a; Tas; mKIAA0213; M3K4_HUMAN; MAP3K4; MAP three kinase 1; MAPK/ERK kinase kinase 4 (MEK kinase 4 | MEKK 4); 2.7.11.25; KIAA0213; M3K4_MOUSE; mitogen-activated protein kinase kinase kinase 4
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
React Species	Human
Applications	IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human MEKK4
Purification	affinity purified by Protein A
Predicted MW.	182 kDa
Observed MW.	190 kDa
Subcellular Location	Cytoplasm
Gene ID	4216
Swiss-Prot	Q9Y6R4
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Paraformaldehyde-fixed, paraffin embedded Human Testicles; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with MAP3K4 Monoclonal Antibody, Unconjugated (SLA2494M) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.	Figure 2. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with MAP3K4 Monoclonal Antibody, Unconjugated (SLA2494M) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.
Figure 3. Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with MAP3K4 Monoclonal Antibody, Unconjugated (SLA2494M) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.	Figure 4. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with MAP3K4 Monoclonal Antibody, Unconjugated (SLA2494M) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.
Figure 5. Paraformaldehyde-fixed, paraffin embedded Human Placenta; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with MAP3K4 Monoclonal Antibody, Unconjugated (SLA2494M) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.