Product Name	Recombinant Rabbit Anti-HP Monoclonal Antibody
Cat No.	SLA0586M
Chinese Name	牛结合珠蛋白单克隆抗体
Alias	BP; HP2ALPHA2; HPA1S; HP-1; preHP2; Ba1-647; HPT_HUMAN; HP; Zonulin; HPT_MOUSE; HPT_RAT; Liver regeneration-related protein LRRG173; haptoglobin
Host Species	Mouse
Isotype	IgG
Clonality	Monoclonal
Clone No.	2H3
React Species	Bovine
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant Bovine Haptoglobin protein
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	45 kDa
Observed MW.	55 kDa
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. 100 ng Recombinant Bovine Haptoglobin protein, C-His (HEK293) (SL43176P) per lane probed with Bovine Haptoglobin monoclonal antibody respectively, unconjugated (SLA0586M) at 1:1000 dilution and 4°C overnight incubation. Followed by corresponding conjugated secondary antibody incubation at r.t. for 60 min.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.