Product Name	Rabbit Anti-GSK3B Polyclonal Antibody
Cat No.	SLA0083
Chinese Name	磷酸化糖原合酶激酶-3β抗体
Alias	7330414F15Rik; 8430431H08Rik; GSK-3; GSK-3beta; GSK3; GSK3B_HUMAN; GSK3B; GSK-3 beta; Serine/threonine-protein kinase GSK3B; 2.7.11.26; GSK3B_MOUSE; glycogen synthase kinase 3 beta; GSK3B | GSK3 beta (phospho-S9); p-GSK3 beta; phospho-GSK3 beta; p-GSK3B; GSK3B | GSK3 beta (phospho-Ser9)
Host Species	Rabbit
Isotype	IgG
Clonality	Polyclonal
React Species	Human
Applications	IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated Synthesised phosphopeptide derived from human GSK-3 Beta around the phosphorylation site of Ser9
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	47 kDa
Subcellular Location	Nucleus
Gene ID	2932
Swiss-Prot	P49841
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Paraformaldehyde-fixed, paraffin embedded (human brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (phospho-GSK3B (Ser9) ) Polyclonal Antibody, Unconjugated (SLA0083) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.