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Product Name Recombinant Rabbit Anti-GPR84 Monoclonal Antibody Cat No. SLA0552M Chinese Name G蛋白偶联受体84重组兔单抗 Alias GPR84_HUMAN; GPR84; Inflammation-related G-protein coupled receptor EX33; EX33; GPCR4; G protein-coupled receptor 84 Host Species Rabbit Isotype IgG Clonality Monoclonal Clone No. 8H14 React Species Human Applications WB (1:500-2000)
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.Immunogen Recombinant human GPR84 protein Purification affinity purified by Protein A Concentration 1mg/ml Predicted MW. 44 kDa Observed MW. 35 kDa Subcellular Location Membrane Gene ID 53831 Swiss-Prot Q9NQS5 Storage 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.Background G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 84 (GPR84), a member of the GCPR 1 family, is an orphan GCPR expressed in bone marrow, brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta, intestine, lung and peripheral blood leukocytes. In activated T cells, GPR84 regulates early interleukin-4 (IL-4) gene expression Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Validation Images
Figure 1. 20 ng rhGPR84-Trx-His protein (SL42242P) per lane probed with GPR84 polyclonal antibody respectively, unconjugated (SLA0552M) at 1:1000 dilution and 4°C overnight incubation. Followed by corresponding conjugated secondary antibody incubation at r.t. for 60 min.
FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.
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[email protected]
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