Product Name	Rabbit Anti-MYO7A Polyclonal Antibody
Cat No.	SLA0099
Chinese Name	肌球蛋白7a/常染色体隐性耳聋蛋白2抗体
Alias	MYO7A_HUMAN; MYO7A; USH1B; DFNA11; DFNB2; MYOVIIA; MYU7A; NSRD2; myosin VIIA; myosin VIIA (Usher syndrome 1B (autosomal recessive, severe))
Host Species	Rabbit
Isotype	IgG
Clonality	Polyclonal
React Species	Mouse,Rat
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human Myosin VIIa
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	254 kDa
Observed MW.	250 kDa
Subcellular Location	Cytoplasm
Gene ID	4647
Swiss-Prot	Q13402
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. In retina, myosin VIIa may play a role in trafficking of ribbon-synaptic vesicle complexes and renewal of the outer photoreceptors disks. In inner ear, it may maintain the rigidity of stereocilia during the dynamic movements of the bundle.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Sample: Lane 1: Mouse Liver tissue lysates Lane 2: Mouse Testis tissue lysates Lane 3: Rat Testis tissue lysates Primary: Anti-Myosin VIIa (SLA0099) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 254 kDa Observed band size: 250 kDa

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.