Product Name	Recombinant Rabbit Anti-ADAM22 Monoclonal Antibody
Cat No.	SLA0693M
Chinese Name	ADAM22单克隆抗体
Alias	ADAM 22; DEE61; EIEE61; MDC2; 2900022I03Rik; ADA22_HUMAN; ADAM22; Metalloproteinase-disintegrin ADAM22-3; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2; ADA22_MOUSE; ADAM metallopeptidase domain 22; a disintegrin and metalloproteinase domain 22
Host Species	Mouse
Isotype	IgG
Clonality	Monoclonal
Clone No.	10C3
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant human ADAM22 protein
Purification	affinity purified by Protein A
Predicted MW.	100 kDa
Observed MW.	65,37 kDa
Subcellular Location	Membrane
Gene ID	53616
Swiss-Prot	Q9P0K1
Storage	Size : 50ul/100ul/200ul 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Size : 200ug (PBS only) 0.01M PBS (pH7.4). Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.[provided by RefSeq, Dec 2010]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Sample: Lane 1: Recombinant human ADAM22 protein(SL49206P) Primary: Anti-ADAM22 (SLA0693M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 100 kDa Observed band size: 65,37 kDa

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.