Product Name	Rabbit Anti-HS6ST1 Polyclonal Antibody
Cat No.	SLA0012
Chinese Name	硫酸乙酰肝素6脑苷脂转硫酸酶1抗体
Alias	HH15; HS6ST; 6Ost1; H6ST1_HUMAN; HS6ST1; HS6ST-1; 2.8.2.-; H6ST1_MOUSE; mHS6ST-1; heparan sulfate 6-O-sulfotransferase 1
Host Species	Rabbit
Isotype	IgG
Clonality	Polyclonal
React Species	Mouse,Rat
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human HS6ST1
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	48 kDa
Observed MW.	55 kDa
Gene ID	9394
Swiss-Prot	O60243
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Heparan sulfate structures, which are responsible for executing multiple biologic activities, are generated and regulated by heparan sulfate (HS) biosynthetic enzymes. HS6ST1 (heparan sulfate 6-O-sulfotransferase 1), also known as HS6ST, is a 411 amino acid single-pass type II membrane protein that exists as multiple alternatively spliced isoforms and belongs to the sulfotransferase 6 family. Expressed in fetal brain, HS6ST1 functions as a 6-O-sulfation enzyme that specifically catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the N-sulfoglucosamine residue (GlcNS) HS. HS6ST1 is subject to post-translational N-glycosylation and is encoded by a functional gene on human chromosome 2 and a pseudogene on human chromosome 1 (known as LOC728969).
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Sample: Lane 1: Mouse Muscle tissue lysates Lane 2: Mouse Liver tissue lysates Lane 3: Rat Spleen tissue lysates Primary: Anti-HS6ST1 (SLA0012) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48 kDa Observed band size: 55 kDa

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.