Product Name	Rabbit Anti-ITGAL Polyclonal Antibody
Cat No.	SLA0184
Chinese Name	整合素αL抗体
Alias	CD11A; LFA-1; LFA1A; ITAL_HUMAN; ITGAL; CD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain (LFA-1A); Leukocyte function-associated molecule 1 alpha chain; integrin subunit alpha L; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); human neutrophil antigen 5; antigen CD11A (p180); lymphocyte function-associated antigen 1, alpha polypeptide
Host Species	Rabbit
Isotype	IgG
Clonality	Polyclonal
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant human CD11a protein
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	126 kDa
Observed MW.	39 kDa
Subcellular Location	Membrane
Gene ID	3683
Swiss-Prot	P20701
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Sample: Lane 1: Recombinant human CD11a protein, N-His(SL42274P) Primary: Anti-CD11a (SLA0184) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 126 kDa Observed band size: 39 kDa

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.