Product Name	Recombinant Rabbit Anti-ARG1 Monoclonal Antibody
Cat No.	SLA1062M
Chinese Name	精氨酸酶1重组兔单抗
Alias	AI; Arg-1; PGIF; ARGI1_BOVIN; ARG1; Liver-type arginase; Type I arginase; 3.5.3.1; ARGI1_HUMAN; ARGI1_MOUSE; ARGI1_PIG; ARGI1_RABIT; ARGI1_RAT; arginase 1; arginase, liver; arginase-1
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	19G6
React Species	Mouse,Rat
Applications	WB (1:1000-5000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human Arginase 1
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	35 kDa
Observed MW.	35-40 kDa
Subcellular Location	Cytoplasm
Gene ID	383
Swiss-Prot	P05089
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Arginase I which is expressed almost exclusively in the liver, catalyzes the conversion of arginine to ornithine and urea . The human arginase I gene, which maps to chromosome 6q23, encodes a 322 amino acid protein. Arginase I exists as a homotrimeric protein and contains a binuclear manganese cluster. Arginase II catalyzes the same reaction as arginase I, but differs in its tissue specificity and subcellular location. Specifically, arginase II localizes to the mitochondria. Arginase II is expressed in non-hepatic tissues, with the highest levels of expression in the kidneys, but, unlike arginase I, is not expressed in liver. The human arginase II gene, which maps to chromosome 14q24.1-q24.3, encodes a 354 amino acid protein. In addition, arginase II contains a putative amino-terminal mitochondrial localization sequence.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. 25 ug total protein per lane of various lysates (see on figure) probed with Arginase 1 monoclonal antibody, unconjugated (SLA1062M) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.