Product Name	Recombinant Rabbit Anti-Cd86 Monoclonal Antibody
Cat No.	SLA0600M
Chinese Name	CD86重组兔单抗
Alias	B7-2; B7.2; B70; CD28LG2; LAB72; CD86_HUMAN; CD86; Activation B7-2 antigen; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD86 molecule; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); B-lymphocyte antigen B7-2
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	10F3
React Species	Mouse
Applications	Flow-Cyt (1:50-100) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant mouse CD86 protein
Purification	affinity purified by Protein A
Predicted MW.	35 kDa
Subcellular Location	Membrane
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.