Product Name	CGB3 | hCG-beta Recombinant Rabbit mAb
Cat No.	SLM-43172R
Chinese Name	人绒毛膜促性腺激素β重组兔单抗
Alias	CGB; CGB5; CGB7; CGB8; LHB; hCGB; CGB3_HUMAN; CGB3; Choriogonadotropin subunit beta (CG-beta); Chorionic gonadotropin chain beta; chorionic gonadotropin subunit beta 3; chorionic gonadotropin, beta polypeptide; chorionic gonadotropin beta subunit 3
Host Species	Rabbit
Isotype	IgG
Clonality	Recombinant
Clone No.	3F4
React Species	Human
Applications	IHC-P (1:200-800) IHC-F (1:200-800) IF (1:200-800) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant human Choriogonadotropin subunit beta 3 protein
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	18 kDa
Observed MW.
Subcellular Location	Secreted
Gene ID	1082
Swiss-Prot	P0DN86
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The beta subunit of chorionic gonadotropin (CGB) is encoded by six highly homologous and structurally similar genes that are arranged in tandem and inverted pairs on chromosome 19q13.3, and contiguous with the luteinizing hormone beta (LHB) subunit gene. The CGB genes are primarily distinguished by differences in the 5' untranscribed region. This gene was originally thought to be one of the two pseudogenes (CGB1 and CGB2) of CGB subunit, however, detection of CGB1 and CGB2 transcripts in vivo, and their presence on the polysomes, suggested that these transcripts are translated. To date, a protein product corresponding to CGB1 has not been isolated. The deduced sequence of the hypothetical protein of 132 aa does not share any similarity with that of functional CGB subunits (PMID:8954017). However, a 155 aa protein, translated from a different frame, is about the same size, and shares 98% identity with other CGB subunits. [provided by RefSeq, Jul 2008]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Paraformaldehyde-fixed, paraffin embedded Human Placenta; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with Human CG beta Monoclonal Antibody, Unconjugated (SLM-43172R) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.

Figure 2. (Negative control) Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with Human CG beta Monoclonal Antibody, Unconjugated (SLM-43172R) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.