Product Name	SERPINB3 | SCCA1/T4-A Mouse mAb
Cat No.	SLM-43190M
Chinese Name	丝氨酸蛋白酶抑制剂B3单克隆抗体
Alias	HsT1196; SCC; SCCA-1; SCCA-PD; SCCA1; SSCA1; T4-A; SPB3_HUMAN; SERPINB3; Protein T4-A; Squamous cell carcinoma antigen 1 (SCCA-1); SCCA; serpin family B member 3; squamous cell carcinoma antigen 1; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 3
Host Species	Mouse
Isotype	IgG
Clonality	Monoclonal
Clone No.	8C9
React Species	Human
Applications	IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant human SERPINB3 protein
Purification	affinity purified by Protein A
Concentration
Predicted MW.	45 kDa
Observed MW.
Subcellular Location	Cytoplasm
Gene ID	6317
Swiss-Prot	P29508
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Enables cysteine-type endopeptidase inhibitor activity; protease binding activity; and virus receptor activity. Involved in several processes, including autocrine signaling; paracrine signaling; and regulation of cellular protein metabolic process. Located in cytoplasmic vesicle; extracellular exosome; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Paraformaldehyde-fixed, paraffin embedded Human Lung squamous cell carcinoma; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(SLM-43190M) at 1:200 overnight at 4°C, followed by conjugation to the SL40296G-HRP and DAB (C-0010) staining.	Figure 2. Paraformaldehyde-fixed, paraffin embedded Human Prostate; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(SLM-43190M) at 1:200 overnight at 4°C, followed by conjugation to the SL40296G-HRP and DAB (C-0010) staining.
Figure 3. Paraformaldehyde-fixed, paraffin embedded Human Esophagus; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SERPINB3 Monoclonal Antibody, Unconjugated(SLM-43190M) at 1:200 overnight at 4°C, followed by conjugation to the SL40296G-HRP and DAB (C-0010) staining.	Figure 4. Paraformaldehyde-fixed, paraffin embedded Human Prostate; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with SERPINB3 Monoclonal Antibody, Unconjugated (SLM-43190M) at 1:200 overnight at 4°C. Followed by conjugated Goat Anti-Mouse IgG antibody (Green, SL0296G-BF488), DAPI (blue, C02-04002) was used to stain the cell nuclei.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.