Tetramethylrhodamine-5-maleimide is a monomer purified from a mixture of tetramethylrhodamine-5(6)-maleimide and is widely used for thiol modification of peptides and proteins. Compared with the 6-isomer，tetramethylrhodamine-5-maleimide is more suitable for sulfur hydroxylation modification of proteins and peptides.

 

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