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Rabbit Anti-SEZ6/AF350 Conjugated antibody
Rabbit Anti-SEZ6/AF350 Conjugated antibody
Brain-specific receptor-like protein C; BSRP-C; hSEZ-6; Seizure protein 6; Seizure protein 6 homolog; Seizure related gene 6; SEZ-6; Sez6; SEZ6_HUMAN.
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  • NO.:SL19673R-AF350
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted:Human,Mouse,Rat)
    Applications:ICC/IF,IF
    concentration:1mg/ml
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Product Name Anti-SEZ6/AF350
Chinese Name AF350标记的癫痫相关基因6抗体
Alias Brain-specific receptor-like protein C; BSRP-C; hSEZ-6; Seizure protein 6; Seizure protein 6 homolog; Seizure related gene 6; SEZ-6; Sez6; SEZ6_HUMAN.
Research Area Cell biology Neurobiology
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted:Human,Mouse,Rat)
Applications ICC/IF=1:50-200,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 105kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SEZ6
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 1M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail Function:
May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor. Involved in the development of appropriate excitatory synaptic connectivity.

Subcellular Location:
Cell membrane. Localized on dendrites and in the synaptic and postsynaptic fraction.

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the SEZ6 family.
Contains 2 CUB domains.
Contains 5 Sushi (CCP/SCR) domains.

Database links:

Entrez Gene: 539038 Cow

Entrez Gene: 124925 Human

Entrez Gene: 20370 Mouse

Entrez Gene: 192247 Rat

SwissProt: A0JNA2 Cow

SwissProt: Q53EL9 Human

SwissProt: Q7TSK2 Mouse

Unigene: 21837 Human

Unigene: 229330 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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