Product Name	Anti-Calumenin/AP
Chinese Name	碱性磷酸酶（AP）标记的钙腔蛋白
Alias	CALU; CALU_HUMAN; Calumenin; Crocalbin; crocalbin-like protein; multiple EF-hand protein.
Research Area	Signal transduction transcriptional regulatory factor Binding protein Cell type markers
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit)
Applications	WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	35kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Calumenin
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 1M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Involved in regulation of vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity. Function: Involved in regulation of vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity. Subunit: Interacts with GGCX. Subcellular Location: Endoplasmic reticulum lumen. Secreted. Melanosome. Sarcoplasmic reticulum lumen. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Tissue Specificity: Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver. Similarity: Belongs to the CREC family. Contains 6 EF-hand domains. Database links: Entrez Gene: 813 Human Entrez Gene: 12321 Mouse Entrez Gene: 64366 Rat Omim: 603420 Human SwissProt: O43852 Human SwissProt: O35887 Mouse SwissProt: O35783 Rat Unigene: 592258 Human Unigene: 7753 Human Unigene: 392075 Mouse Unigene: 1841 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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