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Rabbit Anti-PRRG1/AP Conjugated antibody
Rabbit Anti-PRRG1/AP Conjugated antibody
PRGP1; Proline rich gamma carboxyglutamic acid protein 1; Proline rich Gla (G carboxyglutamic acid) 1; Proline rich Gla (G carboxyglutamic acid) polypeptide 1; Proline rich Gla protein 1; Proline-rich gamma-carboxyglutamic acid protein 1; Proline-rich Gla
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  • NO.:SL19433R-AP
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted:Human,Mouse,Rat,Cow)
    Applications:IHC-P,IHC-F
    concentration:1mg/ml
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Details

Product Name Anti-PRRG1/AP
Chinese Name 碱性磷酸酶(AP)标记的跨膜γ羧基酸蛋白1抗体
Alias PRGP1; Proline rich gamma carboxyglutamic acid protein 1; Proline rich Gla (G carboxyglutamic acid) 1; Proline rich Gla (G carboxyglutamic acid) polypeptide 1; Proline rich Gla protein 1; Proline-rich gamma-carboxyglutamic acid protein 1; Proline-rich Gla protein 1; PRRG1; TMG1; TMG1_HUMAN; Transmembrane gamma carboxyglutamic acid protein 1 [Precursor]; Transmembrane gamma-carboxyglutamic acid protein 1.
Research Area Tumour Cell biology immunology The cell membrane蛋白
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted:Human,Mouse,Rat,Cow)
Applications IHC-P=1:100-500,IHC-F=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 23kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human PRRG1
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 1M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. This gene is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]

Subcellular Location:
Membrane.

Tissue Specificity:
Highly expressed in the spinal cord.

Post-translational modifications:
Gla residues are produced after subsequent post-translational modifications of glutamate by a vitamin K-dependent gamma-carboxylase.

Similarity:
Contains 1 Gla (gamma-carboxy-glutamate) domain.

Database links:

Entrez Gene: 785916 Cow

Entrez Gene: 5638 Human

Entrez Gene: 546336 Mouse

Entrez Gene: 363472 Rat

Omim: 604428 Human

SwissProt: A7Z070 Cow

SwissProt: O14668 Human

Unigene: 190341 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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