Product Name	Anti-PNRC2/AP
Chinese Name	碱性磷酸酶（AP）标记的富含脯氨酸核受体共激活因子2抗体
Alias	0610011E17Rik; D4Bwg0593e; FLJ20312; MGC11707; MGC93828; MGC99541; OTTMUSP00000010360; OTTMUSP00000010366; pnrc2; PNRC2_HUMAN; Proline rich nuclear receptor coactivator 2; Proline-rich nuclear receptor coactivator 2; RP11-4M23.5; RP23-161N17.3.
Research Area	Cell biology Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,Rat(predicted:Human)
Applications	IHC-P=1:100-500,IHC-F=1:100-500 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	16kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PNRC2
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 1M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	Function: Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for UPF1/RENT1 localization to the P-body. Also acts as a nuclear receptor coactivator. May play a role in controlling the energy balance between energy storage and energy expenditure. Subcellular Location: Nucleus. Cytoplasm > P-body. Tissue Specificity: Expressed in heart, lung, muscle and brain. Similarity: Belongs to the PNRC family. PNRC2 subfamily. Database links: Entrez Gene: 100505603 Human Entrez Gene: 55629 Human Entrez Gene: 52830 Mouse Entrez Gene: 100125373 Rat Omim: 611882 Human SwissProt: Q9NPJ4 Human SwissProt: Q9CR73 Mouse SwissProt: Q66HE1 Rat Unigene: 512636 Human Unigene: 644217 Human Unigene: 716935 Human Unigene: 7862 Human Unigene: 29159 Mouse Unigene: 118788 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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