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Rabbit Anti-TRP2/PE-Cy5.5 Conjugated antibody
Rabbit Anti-TRP2/PE-Cy5.5 Conjugated antibody
L dopachrome tautomerase; DCT; DCT; Dopachrome delta isomerase; Dopachrome tautomerase; Dopachrome tautomerase dopachrome delta isomerase, tyrosine related protein 2; DT; EC 5.3.3.12; L dopachrome Delta isomerase; L-dopachrome Delta-isomerase; L-dopachrom
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  • NO.:SL1511R-PE-Cy5.5
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,(predicted: Mouse,Rat,Pig,Rabbit,Sheep,)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-TRP2/PE-Cy5.5
Chinese Name PE-Cy5.5标记的酪氨酸酶相关蛋白2抗体
Alias L dopachrome tautomerase; DCT; DCT; Dopachrome delta isomerase; Dopachrome tautomerase; Dopachrome tautomerase dopachrome delta isomerase, tyrosine related protein 2; DT; EC 5.3.3.12; L dopachrome Delta isomerase; L-dopachrome Delta-isomerase; L-dopachrome tautomerase; TRP 2; TRP-2; TRP2; Tyrosinase related protein 2; Tyrosinase-related protein 2; TYRP2; TYRP2_HUMAN.  
Research Area immunology  Neurobiology  Kinases and Phosphatases  Synthesis and Degradation  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,  (predicted: Mouse, Rat, Pig, Rabbit, Sheep, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 61kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human TRP2
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail Function:
Involved in regulating eumelanin and phaeomelanin levels.

Subunit:
Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.

Subcellular Location:
Melanosome membrane; Single-pass type I membrane protein. Melanocytes and retinal pigmented epithelium.

Tissue Specificity:
Melanocytes and retinal pigmented epithelium.

Similarity:
Belongs to the tyrosinase family.

Database links:

Entrez Gene: 1638 Human

Entrez Gene: 13190 Mouse

Omim: 191275 Human

SwissProt: P40126 Human

SwissProt: P29812 Mouse

Unigene: 301865 Human

Unigene: 19987 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Synthesis and Degradation(Synthesis and Degradation)
酪氨酸酶相关蛋白-2(tyrosinase related protein-2,TRP-2)又称多巴色素互变异构酶,是一种胞质抗原,与白癜风的病理机制有关.

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