Product Name	Anti-GPM6B/PE
Chinese Name	PE标记的神经The cell membraneglycoproteinM6b
Alias	M6b; Neuronal membrane glycoprotein M6b; rhombex 29; GPM6B_HUMAN.
Research Area	Cell biology Developmental biology Neurobiology Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,Mouse,Rat(predicted:Pig,Horse)
Applications	Flow-Cyt=1μg/Test not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	29kDa
Cellular localization	The cell membrane
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GPM6B
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 1M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: GPM6B belongs to the myelin proteolipid protein family and is implicated in neural development. It is expressed in neurons and glia; cerebellar Bergmann glia, in glia within white matter tracts of the cerebellum and cerebrum, and in embryonic dorsal root ganglia. Function: May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake. Subunit: Interacts with SERT. Subcellular Location: Cell membrane; Multi-pass membrane protein (By similarity). Note=Colocalizes with SERT at the plasma membrane Tissue Specificity: Neurons and glia; cerebellar Bergmann glia, in glia within white matter tracts of the cerebellum and cerebrum, and in embryonic dorsal root ganglia. Similarity: Belongs to the myelin proteolipid protein family. Database links: Entrez Gene: 2824 Human Entrez Gene: 14758 Mouse Entrez Gene: 192179 Rat Omim: 300051 Human SwissProt: Q13491 Human SwissProt: P35803 Mouse SwissProt: Q9JJK1 Rat Unigene: 495710 Human Unigene: 222320 Mouse Unigene: 153513 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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