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Product Name Anti-PABPC3/RBITC Chinese Name 罗丹明(RBITC)标记的多聚腺苷酸Binding protein3抗体 Alias PABP-3; PABP3; PABP3_HUMAN; PABPC3; PABPL3; Poly(A) binding protein 3; Poly(A)-binding protein 3; Polyadenylate binding protein 3; Polyadenylate-binding protein 3; RP11-165I9.5; Testis specific poly(A) binding protein; Testis-specific poly(A)-binding protein; tPABP. Research Area Cell biology transcriptional regulatory factor Binding protein Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 70kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PABPC3 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Messenger RNA stability and translation initiation are extensively under the control of poly(A)-binding proteins (PABP). See PABPC1 (MIM 604679) for background information.[supplied by OMIM, Jul 2002]
Function:
Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to PABPC1.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Testis specific.
Similarity:
Belongs to the polyadenylate-binding protein type-1 family.
Contains 1 PABC domain.
Contains 4 RRM (RNA recognition motif) domains.
Database links:Entrez Gene: 5042 Human
Omim: 604680 Human
SwissProt: Q9H361 Human
Unigene: 458280 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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