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Rabbit Anti-POU5F2/RBITC Conjugated antibody
Rabbit Anti-POU5F2/RBITC Conjugated antibody
1700013G10Rik; class 5; DKFZp686P02123; PO5F2_MOUSE; POU domain; POU domain class 5, transcription factor 2; POU5F2; Sperm 1 POU domain transcription factor; Sperm associated POU domain protein 1; SPRM 1; SPRM-1; SPRM1; transcription factor 2.
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Product Name Anti-POU5F2/RBITC
Chinese Name 罗丹明(RBITC)标记的POU5F2蛋白抗体
Alias 1700013G10Rik; class 5; DKFZp686P02123; PO5F2_MOUSE; POU domain; POU domain class 5, transcription factor 2; POU5F2; Sperm 1 POU domain transcription factor; Sperm associated POU domain protein 1; SPRM 1; SPRM-1; SPRM1; transcription factor 2.  
Research Area Cell biology  Developmental biology  transcriptional regulatory factor  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 36kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from mouse POU5F2
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
POU5F2 (POU Domain Class 5, Transcription Factor 2) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding. An important paralog of this gene is POU5F1.

Function:
Transcription factor that binds preferentially to the octamer motif (5'-ATGTTAAT-3'). May exert a regulatory function in meiotic events that are required for terminal differentiation of male germ cell (By similarity).

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in skeletal and cardiac muscles, brain, heart and lung. Little or no detectable expression found in pancreas, kidney, liver or placenta.

Similarity:
Belongs to the POU transcription factor family.
Class-5 subfamily.
Contains 1 homeobox DNA-binding domain.
Contains 1 POU-specific domain.

Database links:

Entrez Gene: 134187 Human

Entrez Gene: 75507 Mouse

SwissProt: Q8N7G0 Human

SwissProt: Q9DAC9 Mouse

Unigene: 678995 Human

Unigene: 443255 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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